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KMID : 0604520220480040295
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Journal of the Society of Cosmetic Scientists of Korea
2022 Volume.48 No. 4 p.295 ~ p.302
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Anti-oxidant, Anti-aging, and Whitening Effects of Viscum album var. coloratum In Vitro
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Hong Chang-Eui
Lyu Su-Yun
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Abstract
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In this study, we investigated the anti-oxidant, anti-aging, and skin whitening effects of Korean mistletoe (Viscum album var. coloratum). The mistletoe fraction was composed of four types: hexane (HX), ethyl acetate (EA), butanol (BU), and methylene chloride (MC). In total phenol content assay, HX showed the highest phenol content among four fractions. In addition, EA significantly increased 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and catalase-like activities, and MC significantly increased superoxide dismutase (SOD)-like activity. When we compared IC50 value in the hyaluronidase and elastase inhibition assay, MC had the lowest IC50. In addition, we also performed tyrosinase inhibition assay to demonstrate the possibility of Korean mistletoe as a cosmetic component. HX showed the highest tyrosinase inhibition rate among the fractions.
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KEYWORD
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korean mistletoe, viscum album var. coloratum, anti-oxidant, anti-aging, whitening
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